6.3 Grammar & Text

6.31 SPELLING, SPELLING, SPELLING

6.32 Try and stay away from serial commas (no commas before and/&):

A pooled analysis of 26 trials including 2,046 pts reported Renaissance (OR 2.86, 95% CI 1.79-4.57) & TiRobot (OR 3.10, 95% CI 2.19-4.40) were assoc w/ higher rates of perfect pedicle screw insertion vs freehand. However, ROSA, SpineAssist, & Orthobot were not. EClinicalMedicine

6.33 No period after abbreviations (except "no."):

A Europainclinics-sponsored 15-pt prosp. cohort study will assess use of 10kHz SCS w/ the Senza SCS System to tx chronic pelvic pain based on pain & disability at 1-, 3-, 6-, 9- & 12-mo f/ups compared to baseline. Est study completion is May 2025. clinicaltrials.gov

6.34 Additional is abbreviated "add'l":

ABT announced Abbott announced the launch of an upgraded version of its NeuroSphere myPath digital health app for Android & Apple devices w/ add’t capability for physicians to track PROMs remotely during a pt trial of an SCS or DRG device to tx chronic

6.35 No trademark or copyright symbols in an update (should read: CybroCell):

FibroBiologics announced an agreement with GEM Global Yield LLC that will provide up to $100.0MM in capital.  The Company’s lead product, CybroCell™, is an allogeneic fibroblast cell therapy for DDD.  The Company has received IND clearance to begin Phase II clinical studies.

6.36 Capitalize the C in company when referring to the primary company in the profile (should read: Company):

FibroBiologics announced an agreement with GEM Global Yield LLC that will provide up to $100.0MM in capital.  The company’s lead product, CybroCell, is an allogeneic fibroblast cell therapy for DDD.  The company has received IND clearance to begin Phase II clinical studies.

6.37 Citing quarters, Q always goes first (should be Q322, not 3Q22):

PSTI completed enrollment in a Phase III study of muscle regeneration following administration of its allogeneic PLX-PAD cell therapy in patients requiring hip arthroplasty. The study enrolled 240 patients from the US, Europe and Israel.  Top line results expected 3Q22.

6.38 Single space after ending a sentence and a new one and don't start a sentence with a number:

A UC Irvine study identified ~1,500 businesses marketing non-FDA approved “stem cell” treatments.  45% involved autologous bone marrow cells, whereas 30% promoted autologous adipose tissue derived cells.  45% promoted txs for orthopedic conditions. Cell Stem Cell

6.39 Don't need "US" in front of dollars (should read: " ...(incremental cost $1,707). This resulted in an ICER of $84,92/QALY.":

In this study, in tx of knee OA, cooled radiofrequency ablation (CRFA) resulted in an incremental QALY gain of 0.020 at an incremental cost of US$1,707, equating to an incremental cost-effectiveness ratio (ICER) of US$84,392/QALY over 6 mo vs HA inj. BMC Musculoskeletal Disorders